Gene Expression of Small Cell Carcinoma of the Ovary, hypercalcemic type.

Small cell carcinoma of the ovary-hypercalcemic type (SCCOHT) is a rare and aggressive form of ovarian cancer afflicting young women at a median age of 24 years. SCCOHTs are characterized by loss of protein expression of SWI/SNF chromatin remodeling ATPases SMARCA4 and SMARCA2 through mutation and epigenetic silencing, respectively. This study aims to establish gene expression profiles of this cancer through RNA-Seq of four pathologically confirmed cases of SCCOHT tumors. RNA-Seq on four SCCOHT tumor tissues NOTE: [1] the raw data for Samples TGEN-A and TGEN-B have been submitted to dbGaP (phs001528.v1.p1; https://www.ncbi.nlm.nih.gov/gap) [2] The submitter does not have consent to submit the raw data for Samples TGEN-C and TGEN-D.