Copper-Mediated Remote C–H Bond Chalcogenation of Quinolines on the C5 Position
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An efficient and convenient method is developed for the remote C–H bond chalcogenation of 8-aminoquinoline scaffolds on the C5 position that is geometrically inaccessible. The protocol makes use of inexpensive CuBr2 as mediator and shows good tolerance toward numerous disulfides/diselenides and aliphatic amides, giving the corresponding products in good to excellent yield.
创建时间：
2016-02-12
