Table 1_Preoperative subjective impairments in language and memory in brain tumor patients.xlsx

BackgroundSubjective reports can reveal relevant information regarding the nature of the impairment of brain tumor patients, unveiling potential gaps in current assessment practices. The co-occurrence of language and memory impairments has been previously reported, albeit scarcely. The aim of this study is therefore to understand the co-occurrence of subjective language and memory complaints in the preoperative state of brain tumor patients and its impact on Quality of Life (QoL).Methods31 brain tumor patients (12 LGG, 19 HGG) underwent a semi-structured interview to assess subjective complaints of language deficits, co-occurrences between language and memory dysfunction, and changes in QoL. Group and subgroup analyses were conducted to provide general and tumor grade specific data.Results48.4% of patients mentioned co-occurrence of language and memory impairments in reading, writing, and conversation. The HGG group reported co-occurrences in all three of these (reading: 31.6%; writing: 21.1%; conversation: 26.3%), while the LGG only described co-occurrences in reading (25%) and conversation (8.3%), although these were not statistically significant. All patients with co-occurring language and memory deficits reported these to be linked to reduced QoL (48.4%). In patients with an HGG, this number was slightly higher (52.6%) than in patients with an LGG (41.7%).ConclusionLanguage impairments co-occur with memory dysfunction as perceived in patients’ daily life. Patients see these impairments as affecting their quality of life. Further attention to dedicated language and memory tasks seems necessary.

背景：主观性报告能够揭示脑肿瘤患者脑功能障碍的性质，揭示当前评估实践中可能存在的缺陷。语言障碍与记忆力减退的并存现象虽已有报道，但较为罕见。因此，本研究旨在探讨脑肿瘤患者在术前状态下主观性语言和记忆力投诉的并存情况及其对生活质量（QoL）的影响。方法：31名脑肿瘤患者（其中12例为LGG，19例为HGG）接受了半结构化访谈，以评估语言缺失的主观投诉、语言与记忆力功能障碍的并存情况以及生活质量的变化。进行了分组和亚组分析，以提供一般性和肿瘤分级特定的数据。结果：48.4%的患者提到了阅读、写作和对话中语言和记忆力减退的并存现象。HGG组在这三个方面都报告了并存现象（阅读：31.6%；写作：21.1%；对话：26.3%），而LGG组仅描述了阅读（25%）和对话（8.3%）中的并存现象，尽管这些并非具有统计学意义。所有并存语言和记忆力缺失的患者均报告这些缺失与生活质量降低（48.4%）相关。在HGG患者中，这一比例略高于LGG患者（52.6% vs 41.7%）。结论：患者日常生活中的语言障碍与记忆力功能障碍并存。患者认为这些障碍影响了他们的生活质量。对专门的语言和记忆力任务的进一步关注似乎显得必要。