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Crystal structure of the second bromodomain (BD2) of human BRD3 bound to BI2536

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of the second bromodomain (BD2) of human BRD3 bound to BI2536 Descriptor: 1,2-ETHANEDIOL, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Bromodomain-containing protein 3 Authors: Karim, M.R, Bikowitz, M.J, Schonbrunn, E. Deposit date: 2021-01-04 Release date: 2021-07-07 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors. J.Med.Chem., 64, 2021

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2021-01-04
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