Synthesis and Fucosidase Inhibitory Study of Unnatural Pyrrolidine Alkaloid 4-<i>epi</i>-(+)-Codonopsinine
收藏NIAID Data Ecosystem2026-03-07 收录
数据链接：
官方服务：
资源简介：
The total synthesis of enantiopure 4-epi-(+)-codonopsinine was achieved in 10 steps starting from d-ribose as a chiral building block. The key step involved a highly stereoselective nucleophilic addition of a Grignard reagent to a protected ribosylamine. Synthesis of the N-desmethyl derivative and its p-tolyl analogue was also accomplished, and the compounds were assayed against α-fucosidase.
创建时间：
2011-05-20
