Background: Fucoidan (FPS) has been widely used to treat renal fibrosis (RF) in patients with diabetic kidney disease (DKD); however, the precise therapeutic mechanisms remain unclear. Recently, resea
Human atherosclerosis single-cell transcriptome analysis revealed that GSDME is mainly expressed in macrophages. In vitro, ox-LDL induces the expression of GSDME and pyroptosis in macrophages.