The germline encoding of a non-immune immunoglobulin M (IgM) molecule in mammals was experimentally documented for the first time as a result of the specifically timed ovariectomy of C57BL/10 mice. Th
Sympathetic ophthalmia (SO) is considered as an autoimmune disease with unclear mechanisms. This study investigated the relationship between HLA polymorphisms and SO. HLA typing was performed using th
C1R cells expressing MICA*001 or MICA*008 were loaded with PKH67 and added to macrophages in the presence of a range of doses of MICAB1 Fc-engineered or isotype control mAb. The cells were incubated f
Anti-cytokine autoantibodies (ACAAs) have been described in a growing number of primary immunodeficiencies with autoimmune features, including autoimmune polyendocrine syndrome type I (APS-1), a proto
