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Variants in tubule epithelial regulatory elements mediate most heritable differences in human kidney function

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE262931
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We used bulk and single-cell ATAC-seq to measure chromatin accessibilty in human kidneys. This allowed us to define candidate cis-regulatory elements of each human kidney cell type and identify the role of podocyte and tubule regulatory elements in human kidney function. Single cell ATAC-sequencing of 3 human kidneys. Single cell ATAC-sequencing was performed on cortex from all 3 kidneys and medulla from two of the kidneys. Bulk ATAC-sequencing from the cortex of one human kidney was also performed. **Please note that the records have been updated with additional data on Aug 8, 2024.****
创建时间:
2024-09-26
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