Gene expression profile in wild red-crowned crane liver. Grus japonensis

Red-crowned crane (Grus japonensis) is an endangered species. The limitation of its habitat range and the low genetic diversity as a consequence of recovering from a bottleneck highlight the extinction risk from chemical pollution throughout the habitat. To understand drug sensitivity in red-crowned cranes is important for determining the treatment protocol in this endangered species. An important factor determining drug sensitivity is the ability to metabolize xenobiotics. Liver is one of the most important organ in xenobiotic metabolism and the profile of gene expression in the liver of red-crowned crane helps to understand drug sensitivity. This project aim to clarify the ability of xenobiotic metabolism.