Crystal structure of the Kelch domain of human KLHL12 with compound 10q
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Crystal structure of the Kelch domain of human KLHL12 with compound 10q Descriptor: 2-{4-[(1R,2S)-2-{[(3S)-3-(1,1-dioxo-1lambda~6~-thiomorpholin-4-yl)pyrrolidin-1-yl]methyl}cyclopropyl]-2-methyl-1H-1,3-benzimidazol-1-yl}-N-(2,4,6-trichlorophenyl)acetamide, Kelch-like protein 12 Authors: Amporndanai, K, Madrigal-Carrillo, E.A, Rietz, T.A, Zhao, B, Fesik, S.W. Deposit date: 2025-09-11 Release date: 2026-04-08 Last modified: 2026-04-22 Method: X-RAY DIFFRACTION (1.271 Å) Cite: Identification of KLHL12 Ligands Using Fragment-Based Methods. J.Med.Chem., 69, 2026
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2025-09-11
