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Extracellular Vesicles Derived from Inflammatory Cardiomyocytes Mediate Macrophage Polarization and Alleviate Myocarditis via p38 MAPK Pathway

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NIAID Data Ecosystem2026-05-02 收录
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EVs derived from lipopolysaccharide (LPS)-stimulated cardiomyocytes (EVLPS) exhibit anti-inflammatory effects on macrophages and reduce cardiac inflammation in mice.To investigate gene expression changes induced by EVLPS treatment in inflammatory RAW264.7 using next-generation sequencing,we performed RNAseq. mRNA profiles of LPS-stimulated RAW264.7 treated with either EVLPS or PBS were generated by deep sequencing, in quadruplicate

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2024-10-23
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