Area under the curve (AUC) NONMEM estimate values for ABCB1 c. 4046A>G and or CYP2B6* 6 genotypes.

The estimations are based on the predicted individual apparent clearance and bioavailability values.
mut = heterozygous plus homozygous variant, wt = homozygous variants.
Four patients did not have a reported ABCB1 genotype and one patient was ABCB1 G/G. These five subjects are not included in these summary statistics for ABCB1, but are included in the general CYP2B6*6 summary above.