Reduced a-MSH underlies hypothalamic endoplasmic reticulum stress-induced hepatic gluconeogenesis

ChEBI2015-06-18 更新2026-07-12 收录

神经内分泌代谢调控

肝脏糖异生

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62263 数据链接链接失效反馈

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Reduced a-MSH underlies hypothalamic endoplasmic reticulum stress-induced hepatic gluconeogenesis

创建时间：

2015-06-18

Additional file 2: of Reductions in hypothalamic Gfap expression, glial cells and α-tanycytes in lean and hypermetabolic Gnasxl-deficient mice

神经内分泌代谢调控

基因表达功能富集分析

Functional enrichment analysis using the DAVID bioinformatics resources. The whole mouse genome was used as background with default parameter settings. Full results, including p-values after correctin

NIAID Data Ecosystem50

Table_9_Involvement of POMC neurons in LEAP2 regulation of food intake and body weight.xlsx

神经内分泌代谢调控

食欲与体重调节机制

Liver-expressed antimicrobial peptide 2 (LEAP2) is a newly discovered antagonist of the growth hormone secretagogue receptor (GHSR) and is considered the first endogenous peptide that can antagonize t

NIAID Data Ecosystem40

Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids. Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids

代谢调控

肝脏糖异生

Hepatic gluconeogenesis from amino acids contributes significantly to diabetic hyperglycemia, but the molecular mechanisms involved are incompletely understood. Alanine transaminases (ALT1 and ALT2) c

NIAID Data Ecosystem30

Hypothalamus-sympathetic-liver axis mediates the early phase of stress-induced hyperglycemia

应激性高血糖

神经内分泌代谢调控

In this dataset, we present the stress-induced hyperglycemia in the different stages. Specifically, a hypothalamus (paraventricular to ventromedial hypothalamus)-sympathetic (raphe pallidus nucleus to

Figshare2024-10-05 更新50

Hepatic Interferon Regulatory Factor 3 Fuels Gluconeogenesis via PP2A-mediated Inactivation of AMP Kinase

肝脏糖异生

IRF3转录组学

We report the IRF3 transcriptome and cistrome in primary mouse hepatocytes. RNA-seq and IRF3 CUT&RUN was performed in primary mouse hepatocytes expressing constitutively active IRF3 (IRF3-2D) and cont

NIAID Data Ecosystem40

Reduced a-MSH underlies hypothalamic endoplasmic reticulum stress-induced hepatic gluconeogenesis

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