STAT1 and IRF1 enrichment in naive and primed HeLa cells upon IFNγ treatment

ChEBI2023-05-06 更新2026-07-12 收录

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转录因子富集

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STAT1 and IRF1 enrichment in naive and primed HeLa cells upon IFNγ treatment

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2023-05-06

The effect of type I IFN treatment on global gene expression in monocytes undergoing maturation

细胞分化调控

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To analyze the effect of type I IFN on global gene expression in differentiating monocytes, we employed microarray-based gene expression profiling. The MACS-purified mouse BM monocytes were cultured i

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CD95/Fas increases stemness in cancer cells by inducing a STAT1 dependent Type I interferon response [ChIP-seq]

癌细胞调控

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CD95 was found to be important for both the formation of CSCs and their maintenance. Using a stable isotope labeling by amino acids in cell culture (SILAC) analysis we have now identified STAT1 as a

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Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome III

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唐氏综合症治疗

Individuals with Down syndrome have a increased likelihood of suffering from inflammatory and autoimmune conditions, due to the presence of four interferon receptors on chromosome 21. Transcription of

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INTERFEROME: the database of interferon-regulated genes

干扰素诱导基因

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THE DATABASE OF INTERFERON-REGULATED GENES This database is an upgrade of the original Interferome database and contains type I, II and III interferon-regulated genes, manually curated from publicly a

Monash University Figshare2026-02-11 更新80

Epigenome profiling reveals significant DNA demethylation of interferon signature genes in lupus neutrophils

系统性红斑狼疮

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We identified genome-wide DNA methylation patterns within neutrophils and low-density granulocytes of Lupus patients and demographically matched controls Comparison of 15 Lupus patients vs 15 age-, se

NIAID Data Ecosystem70

STAT1 and IRF1 enrichment in naive and primed HeLa cells upon IFNγ treatment

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