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Lactate Dehydrogenase A in complex with inhibitor compound 22

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Protein Data Bank Japan2023-11-15 更新2026-03-21 收录
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Lactate Dehydrogenase A in complex with inhibitor compound 22 Descriptor: (2R)-2-{[5-cyano-4-(3,4-dichlorophenyl)-6-oxo-1,6-dihydropyrimidin-2-yl]sulfanyl}-N-(4-sulfamoylphenyl)propanamide, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... Authors: Eigenbrot, C, Ultsch, M. Deposit date: 2013-03-15 Release date: 2013-05-22 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.896 Å) Cite: Identification of substituted 2-thio-6-oxo-1,6-dihydropyrimidines as inhibitors of human lactate dehydrogenase. Bioorg.Med.Chem.Lett., 23, 2013

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2013-03-15
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