Human PDE9 in complex with selective compound
收藏Protein Data Bank Japan2024-02-28 更新2026-03-21 收录
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Human PDE9 in complex with selective compound Descriptor: 1-cyclopentyl-6-{(1R)-1-[3-(pyrimidin-2-yl)azetidin-1-yl]ethyl}-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, MAGNESIUM ION, ... Authors: Liu, S. Deposit date: 2012-07-12 Release date: 2013-05-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3 Å) Cite: Application of structure-based drug design and parallel chemistry to identify selective, brain penetrant, in vivo active phosphodiesterase 9A inhibitors. J.Med.Chem., 55, 2012
创建时间:
2012-07-12



