XBP1 is the transcriptino factor that is activated by the ER stress. XBP1 is known to induce the ER dexpansion and increase the expression of the ER chaperone genes to prtect the cell from the ER stre
Slowing down protein synthesis, increasing protein folding capability, and enhancing misfolded protein degradation are the main mechanisms of unfolded protein response (UPR) to lessen ER stress. It ha
Cells respond to endoplasmic reticulum (ER) stress through activation of signaling pathways such as the Unfolded Protein Response (UPR) which improve the ER folding environment capacity upon changes i
This dataset contains data used to generate panels 1C and 1D for GRP94, Hsp90 and Hsp40 in a preprint manuscript from the Misteli Lab at the National Cancer Institute/NIH. Title: Activation of endopla
