PectAge: Age-related effects on gut microbiota by pectin

The study investigated whether supplementation of pectin has potential to improve aging-associated dysbiosis of the gut microbiota. The influence of different molecular sizes of pectins on the gut microbiota composition of elderly was compared to younger adults. Additionally, inulin was used as a reference prebiotic substrate. In vitro fermentations were performed using ta batch fermentation model with controlled temperature and pH. Samples were withdrawn at baseline and after 24 h fermentation for checking microbiota composition by 16S rRNA gene sequencing (Nanopore).