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File S1 - Synthesis and Properties of a Selective Inhibitor of Homeodomain–Interacting Protein Kinase 2 (HIPK2)

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Table S1, Selectivity profiles of TBID on a 125 kinase panel. These are expressed in % activity of the enzyme. Figure S1, Synthesis of 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)isoindoline-1,3-diones. Reagents and conditions: (i) acetic acid, reflux, 1–3 h, 11–64%. For synthesis of 5a, instead of a free heterocyclic base the 2-aminoimidazolium sulfate was used in the presence of DBU. (DOC)

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2015-12-02
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