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p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9318

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Protein Data Bank Japan2024-01-17 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6ggb
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p53 cancer mutant Y220C in complex with small-molecule stabilizer PK9318 Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cellular tumor antigen p53, ... Authors: Joerger, A.C, Bauer, M.R. Deposit date: 2018-05-03 Release date: 2019-05-22 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.32 Å) Cite: A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. Future Med Chem, 11, 2019
创建时间:
2018-05-03
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