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KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation (ATAC-Seq)

NIAID Data Ecosystem2026-03-12 收录

T细胞分化表观遗传调控

ATAC-Seq染色质可及性分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166482 数据链接链接失效反馈

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资源简介：

We report on the dynamic regulation of H3K27me3 demethylation during early T cell activation Examination of chromatin accessibility across 3 time points within 1 cell type

应用场景：

创建时间：

2021-06-16

T细胞分化表观遗传调控

染色质构象Hi-C分析

CTCF is known to mediate long range chromatin intearction and 3D genome organization. In CD8+ T cells responding to actue infection, CTCF is redistributed to induce the the cytotoxic program while usi

NIAID Data Ecosystem100

HCP5 inhibits apoptosis via c-Myc transcriptional regulation mediated by UTP3 based chromatin-RNA-binding protein interaction [ATAC-Seq]

癌细胞凋亡调控

ATAC-Seq染色质可及性分析

This study demonstrates that HCP5/UTP3/c-Myc/VAMP3 axis plays important role in inhibition of cancer cell apoptosis and HCP5 can be targeted to contribute to cell apoptosis induced by cytotoxic agents

NIAID Data Ecosystem40

Identification of an enhancer that regulates DNA demethylation-dependent Cd4 expression following thymocyte positive selection. Mus musculus

T细胞分化表观遗传调控

CD4基因表达调控

The inheritance of gene expression patterns is dependent on epigenetic regulation, but the establishment and maintenance of epigenetic landscapes during T cell differentiation are incompletely underst

NIAID Data Ecosystem30

ATAC-Seq using native and iPSC-derived murine retina at three developmental stages.. ATAC-Seq using native and iPSC-derived murine retina at three developmental stages.

发育表观遗传学

ATAC-Seq染色质可及性分析

To identify epigenetic programs underlying differentiation of mouse retina, we performed ATAC-Seq on bulk native retina (NaR) and iPSC-derived 3D retinal aggregates (3D-RA) at three matched stages of

NIAID Data Ecosystem90

MOESM5 of Establishment of regulatory elements during erythro-megakaryopoiesis identifies hematopoietic lineage-commitment points

造血表观遗传学

ATAC-Seq染色质可及性分析

Additional file 5. Peak data from ATAC-Seq experiments. The presence of ATAC-Seq peaks in each cell type is indicated by a 1 (present) or 0 (not present).

NIAID Data Ecosystem30

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation (ATAC-Seq)

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