SMAD1 promoter hypermethylation and lack of SMAD1 expression in Hodgkin Lymphoma. SMAD1 promoter hypermethylation and lack of SMAD1 expression in Hodgkin Lymphoma

Global gene expression analysis was performed of several cell lines, mostly classical Hodgkin lymphoma, one DLBCL cell line and one NLPHL cell line. Overall design: Cells were cultured according to standard conditions, harvested, underwent RNA extraction and gene expression profiling was performed using the Affymetrix Gene Array