Gut microbiota-derived N-acetyl-D-glucosamine alleviates systemic inflammatory responses induced by acute Toxoplasma gondii infection

Toxoplasma gondii, a widespread foodborne protozoan parasite, infects nearly all warm-blooded animals and often causes severe inflammatory tissue damage. Based on the interplay between gut microbiota and host immunity, this study explores the metabolic regulatory networks of the gut microbiome during T. gondii infection by using acute infection models with wild-type and low-virulence strains.