Fine particulate matter (PM2.5) promotes IgE-mediated mast cell activation through ROS/Gadd45b/JNK axis
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164537
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Background: Mast cells play an important role in allergic responses and persistently exposure to environmental fine particulate matter (PM2.5) exacerbates allergic diseases,but the details remain elucidative. Conclusions: PM2.5 regulates ROS production through Gadd45b/MEKK4/JNK pathway, facilitating IgE-mediated mast cell activation. RBL-2H3 cell with Normal saline and PM2.5 plus IgE+DNP-HSA
创建时间：
2021-01-12
