CaSR modulator in neuroblastoma model [mouse]

NIAID Data Ecosystem2026-03-10 收录

胶质母细胞瘤药物研究

CaSR调节剂

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE73506 数据链接链接失效反馈

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资源简介：

CaSR modulation inhibits neuroblastoma growth 8 control and 8 samples treated with CaSR allosteric activator

创建时间：

2018-03-08

Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment

GPR17激动剂设计

胶质母细胞瘤药物研究

The discovery of a potential ligand-targeting G protein-coupled receptor 17 (GPR17) is important for developing chemotherapeutic agents against glioblastoma multiforme (GBM). We used the integration o

Figshare2021-07-26 更新80

Effect of GSK3368715 on GBM patient samples, kept in a novel perfusion device for 8-days

胶质母细胞瘤药物研究

肿瘤微环境

Glioblastoma patient samples were microdissected into ~20mg pieces and put onto a novel perfusion device, within an hour of resection. Samples were left for 8 days, at a flow rate of 3ul/min, with a m

NIAID Data Ecosystem20

DataSheet1_Cinobufagin Is a Selective Anti-Cancer Agent against Tumors with EGFR Amplification and PTEN Deletion.PDF

EGFR驱动肿瘤靶向治疗

胶质母细胞瘤药物研究

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor, and almost half of the patients carrying EGFR-driven tumor with PTEN deficiency are resistant to EGFR-targeted therapy. EGFR

NIAID Data Ecosystem20

High-throughput 3D glioblastoma model for rapid personalized therapeutic screening

胶质母细胞瘤药物研究

个性化医疗

Glioblastoma (GBM) is a devastating brain tumor with limited therapeutic success, largely due to the inability to pre-test patient-specific responses to treatment in a reliable and timely manner with

NIAID Data Ecosystem40

RNA-Seq of U251 glioblastoma cell line with and without (-)-SDS-1-021.

胶质母细胞瘤药物研究

mRNA翻译调控

RNA-Seq analyses polysome-bound mRNAs of glioblastoma cell line NSC11 after 10nM (-)-SDS-1-021 treatement to evaluate drug-induced changes in mRNA translation Vehicle Control (3), 10nM (-)-SDS-1-021 (

NIAID Data Ecosystem20

CaSR modulator in neuroblastoma model [mouse]

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