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snRNAseq of Cpt1a-conditionally-depleted murine kidneys aged with high fat diet

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NIAID Data Ecosystem2026-05-02 收录
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To compare the snRNA seq transcriptional profile in renal tubule cells after conditional deletion of Cpt1a to floxed littermate controls, in mice fed a high fat diet for 2 years, and to compare mice aged 2 years with high fat diet to young mice. Overall design: Cpt1a-floxed mice and mice conditionally depleted of Cpt1a with Pax8-rTTA;tetO-Cre transgenes aged 2 years with high fat diet or aged 3 months were analyzed and compared by snRNA seq. *************************************************************** The table below lists GEO accessions reused/reanalyzed for this study. ***************************************************************

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2025-06-17
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