Table S1 - Polymorphisms in Thioredoxin Reductase and Selenoprotein K Genes and Selenium Status Modulate Risk of Prostate Cancer

Pathway-wise genotyping for SNPs in selenoprotein and related genes in control and prostate cancer patients from the EPIC-Heidelberg cohort. A custom chip was designed for genotyping across the whole pathway; the SNPs analysed and the corresponding genes are shown in the two left columns. Genotyping was carried out on 94 advanced cases and 94 control. Statistical evaluation of main effects of genetic variants on prostate cancer risk was carried out using either co-dominant and dominant models and data stratified for case set. (DOC)