Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul
The data includes NGS data analyses from CRISPR-Cas9 knockout screens for 47 human cancer cell lines, performed with PoolQ (v2.2.0). This output includes raw read counts of sgRNAs and corresponding qu
The effect of miRNA delivery from glomerular endothelial cells (GEnCs) to podocytes in vitro was examined by miRNA epression in podocytes untreated and treated with extracellular vesicles from GEnCs u
NODAL signalling is required to maintain pluripotency in human embryonic stem cells, by maintaining expression of transcription factor NANOG. We treated human blastocysts with NODAL signalling inhibit