This study investigated the effects of inhibiting protein arginine methyltransferases (PRMTs) on immunomodulatory gene expression using in vitro breast cancer models. Breast cancer cell lines (MDA-MB-
The B cell IC50 is given in μM and is the mean of 4 independent experiments. The therapeutic index relates toxicity to activity. B cell Therapeutic index (B cell TI) is the ratio between the toxic con
Cross-presentation of tumor antigens by dendritic cells (DCs) is crucial to prime and (re-) stimulate CD8+ T cells. This process is important in initiating and maintaining an anti-tumor response. Here