胃癌数据分析

胃癌是一种起源于胃黏膜上皮的恶性肿瘤，其预后相对较差，而且癌症往往会提早扩散到其他部位。本产品提供DNA、RNA的分析流程以及单细胞的分析流程。其中DNA包含点突变、结构变异、融合分析、CNV变异分析。RNAseq除了基因表达差异外，还包括新转录本发现、等位基因特异性表达、转录本和非编码RNA的相互作用。单细胞分析包括细胞类别鉴定、细胞间通讯、单细胞轨迹分析、转录因子的分析。

Gastric cancer is a malignant tumor originating from the gastric mucosal epithelium, with relatively poor prognosis and often early metastasis to other tissues and organs. This product provides analytical workflows for DNA, RNA, and single-cell studies. For DNA analysis, it covers point mutations, structural variations, gene fusion detection, and copy number variation (CNV) analysis. For RNA-seq analysis, in addition to differential gene expression, it also includes de novo transcript discovery, allele-specific expression, and the interaction between transcripts and non-coding RNAs. Single-cell analysis includes cell type identification, intercellular communication analysis, single-cell trajectory analysis, and transcription factor analysis.

搜集汇总

背景与挑战

背景概述

该数据集由上海芯超数据科技有限公司提供，专注于胃癌的基因组学分析。它整合了DNA（点突变、结构变异、融合、CNV）、RNA（基因表达差异、新转录本发现、等位基因特异性表达）及单细胞分析（细胞类别鉴定、细胞通讯、轨迹分析、转录因子）等多层次数据，每月动态更新，旨在支持胃癌的预后评估和扩散机制研究。