Accumulation of cytokines, chemokines and growth factors in whole blood.
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ELISA analysis showed that ATG induced a significant dose dependent increase in the secretion of pro- and anti-inflammatory cytokines compared to untreated PBMC after 24 hours of culture. To an even greater extent the release of pro-angiogenic chemokines (e.g. IL-8, GRO-alpha, ENA-78, MCP-1) was triggered. The use of an IVIG preparation failed to initiate the secretion of the aforementioned factors. *p<0.05 vs. 24 h. †p<0.01 vs. 24 h. ‡p<0.001 vs. 24 h.
创建时间：
2012-12-20
