AMPK bound to allosteric activator
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AMPK bound to allosteric activator Descriptor: 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase subunit beta-1, 5'-AMP-activated protein kinase subunit gamma-1, ... Authors: Calabrese, M.F, Kurumbail, R.G. Deposit date: 2016-07-05 Release date: 2016-08-17 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.41 Å) Cite: Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of Adenosine Monophosphate-activated Protein Kinase (AMPK), for the Potential Treatment of Diabetic Nephropathy. J.Med.Chem., 59, 2016
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2016-07-05
