George Richenberg PhD thesis - Supplementary table 6.12: Summary statistics for sfFDR-identified novel genome-wide significant (FP<5x10-8), independent lead variants associated with overall (inc), overall (exc), DNMT3A-, TET2- and ASXL1-mutant CH compared with genetically predicted plasma proteins commonly implicated in AML

Summary statistics for novel, genome-wide significant (FP<5×10⁻⁸), independent lead variants associated with CH risk identified using the sfFDR method in individuals of European ancestry (25,657 cases and 342,869 controls). These variants were compared with summary statistics for germline genetic variants associated with plasma protein levels from seven proteins involved in progression to AML (CEBPA, FLT3, FLT3LG, KIT, KITLG, NPM1 and TP53) that were obtained from a GWAS of 54,219 individuals of European ancestry in the UK Biobank (PMID: 37794186).