Data-and-Code-for-BKGN-Mixture-Exposure-and-Cardiopulmonary-Health-Manuscript

Data and code supporting “Air Purifier Use Shapes Human Cardiopulmonary Responses to Airborne Pollutant Mixtures” This repository contains the supplementary data and analysis/visualization code supporting the manuscript “Air Purifier Use Shapes Human Cardiopulmonary Responses to Airborne Pollutant Mixtures.” The study integrates repeated-measures environmental exposure data, cardiopulmonary health indicators, DNA methylation-derived biological information, and curated toxicological knowledge to construct an exposure–Gene Ontology (GO)–outcome network and perform mechanism-informed prioritization of environmental chemical mixtures. The deposited data include the intermediate and processed datasets used for association analyses, biological network construction, pathway-informed feature engineering, network topology characterization, and visualization. The accompanying R code and input files are provided to facilitate reproduction of the principal figures and network-based analyses reported in the manuscript.