Zenodo: SPIRIT checklist - Experimental evaluation of retinoprotective activity of the polyherbal compound and adjunct effect of ayurvedic intervention and conventional standard of care in pramehaja timira w.s.r. non-proliferative diabetic retinopathy - A double arm exploratory trial.

This entry provides the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) checklist for the registered study titled: “Experimental evaluation of retinoprotective activity of the polyherbal compound and adjunct effect of Ayurvedic intervention and conventional standard of care in Pramehaja Timira (non-proliferative diabetic retinopathy) – A double-arm exploratory trial.” The checklist outlines the protocol compliance with SPIRIT 2013 guidelines, ensuring transparency and methodological rigor in clinical trial planning and reporting. The study investigates the adjunctive efficacy of a polyherbal Ayurvedic formulation combined with conventional standard care in managing NPDR. Key protocol elements including trial design, participant eligibility, intervention details, outcome measures, randomization, data management, and ethical considerations are itemized as per SPIRIT recommendations. This SPIRIT checklist supports the broader goal of reproducibility, protocol harmonization, and integrative research transparency, and is intended to aid peer reviewers, researchers, and regulatory bodies in evaluating the study’s methodological robustness.