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Construct design for the crystallisation of huntingtin fragments - 2018/06/11

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https://zenodo.org/record/1307217
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Project - Huntingtin structure-function open lab notebook.  Objective - Use the cryo-EM structure of huntingtin in complex with HAP40 http://www.rcsb.org/structure/6EZ8 to guide construct design of discrete domains and fragments which could be amenable to successful expression and purification of monodisperse protein samples and subsequent structure solution by X-ray crystallography.
创建时间:
2024-08-02
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