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oncoEnrichR use cases

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Zenodo2023-06-17 更新2026-05-25 收录
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Two use cases demonstrating the functionality of oncoEnrichR for gene list interpretation and hit prioritization. ### Use case analyses - oncoEnrichR This Zenodo repository hosts two use case output reports from<br> [oncoEnrichR](https://github.com/sigven/oncoEnrichR), a dedicated tool for gene<br> set interpretation in cancer. Directory structure: * __`reports`__ - holds pre-computed HTML reports and Excel workbooks for<br> two use cases: 1. FGFR1 network (protein proximity screen)<br> - `fgfr1_network_oncoEnrichR.v1.3.2.html`<br> - `fgfr1_network_oncoEnrichR.v1.3.2.xlsx`<br> 2. EGFR drug resistance drivers (CRISPR screen)<br> - `egfr_drug_resistance_oncoEnrichR.v1.3.2.html`<br> - `egfr_drug_resistance_oncoEnrichR.v1.3.2.xlsx` * __`input`__ - holds input data for the two use cases<br> 1. fgfr1_network_input.tsv<br> 2. egfr_drug_resistance_input.tsv * __`docker`__ - holds input and code for re-running use case analyses through<br> a Docker container __Docker instructions__ - [Install Docker](https://docs.docker.com/get-docker/) on your local computer/client (OS X/Linux)<br> - Download the `input` and `output` directory of the `docker` directory to your local computer/client<br> - Pull the Docker image with the following Docker command on the command-line:<br> * `docker pull sigven/oeusecase:latest`<br> - Run the use case analyses with the following Docker command:<br> * `docker run --rm -ti -v &lt;LOCAL_DIRECTORY&gt;/input:/input -v /LOCAL_DIRECTORY/output:/output sigven/oeusecase:latest`<br> - _NOTE_: replace `LOCAL_DIRECTORY` with the full path on your local computer where you have downloaded the `input` and `output` folders<br> * The above command will generate HTML reports and Excel workbooks for the two use cases in the `output` directory

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Zenodo
创建时间:
2022-10-10
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