RNA-seq of rat microglia, mouse neurons and human astrocytes in co-culture, both in control conditions and challenged with LPS.. RNA-seq of rat microglia, mouse neurons and human astrocytes in co-culture, both in control conditions and challenged with LPS.

We investigated non-cell-autonomously regulated gene expression in microglia, neurons and astrocytes by co-culturing these cell types (derived from different mammalian species) together, and then separating the RNA-seq reads from each cell type/species in silico.