Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain

Obese rats were calorically restricted with (EX) or without (SED) treadmill exercise (1 h/day, 6 days/wk, 15 m/min) to induce and maintain weight loss. After 6 weeks of WLM, subsets of WLM-SED and WLM-EX rats were allowed ad libitum access to food for 1 day to promote relapse (REL). An energy gap-matched group of sedentary, relapsing rats (REL-GM) were provided a diet matched to the positive energy imbalance of the REL-EX rats. Overall design: This dataset is RNA-sequencing performed on the relapsing animals only.