DNA-seq or genomic RNA region of HIV-1 reverse transcriptase, protease and integrase gene

ChEBI2023-11-30 更新2026-07-12 收录

HIV-1耐药性

病毒基因靶点测序

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-13563 数据链接链接失效反馈

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资源简介：

DNA-seq or genomic RNA region of HIV-1 reverse transcriptase, protease and integrase gene

创建时间：

2023-11-30

Human Immunodeficiency Virus Type 1 Protease Genotypes and In Vitro Protease Inhibitor Susceptibilities of Isolates from Individuals Who Were Switched to Other Protease Inhibitors after Long-Term Saquinavir Treatment

HIV-1耐药性

蛋白酶抑制剂交叉耐药

An understanding of the mechanisms of virologic cross-resistance between human immunodeficiency virus type 1 protease inhibitors is important for the establishment of effective treatment strategies fo

PubMed Central40

Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of the viral protease.

HIV-1耐药性

抑制剂筛选

Inhibitors of the human immunodeficiency virus type 1 (HIV-1) protease represent a promising addition to the available agents used to inhibit virus replication in a therapeutic setting. HIV-1 is capab

PubMed Central1994-06-07 更新30

3′-Azido-3′-Deoxythymidine (AZT) and AZT-Resistant Reverse Transcriptase Can Increase the In Vivo Mutation Rate of Human Immunodeficiency Virus Type 1

HIV-1耐药性

抗病毒药物突变效应

How antiretroviral drug resistance influences human immunodeficiency virus type 1 (HIV-1) evolution is not clear. This study tested the hypothesis that antiretroviral drugs such as 3′-azido-3′-deoxyth

PubMed Central20

Validation of publicly-available software used in analyzing NGS data for HIV-1 drug resistance mutations and transmission networks in a Washington, DC, Cohort

HIV-1耐药性

传播网络

We demonstrated excellent correlation between the HyDRA Web pipeline, a free, publicly-available software used to analyze NGS data for detecting DRMs and generating DRM interpretation reports. sing th

NIAID Data Ecosystem40

Background information and neutralization sensitivity of broadly resistant HIV-1 strains.

HIV-1耐药性

抗体中和实验

Background information and neutralization sensitivity of broadly resistant HIV-1 strains.

Figshare2019-06-13 更新30