Effects of various administrations upon hemodynamics in a model of ischemia–reperfusion in rats.

Data are the mean ± SD. Values marked with &&P<0.01 are significantly different from I/R. Values marked with * P<0.05 or ** P<0.01 are significantly different from metoprolol. Values marked with †P<0.05 or ‡P<0.01 are significantly different from baseline. LVSP, LVEDP and ± dp/dtmax represent left ventricular systolic pressure, left ventricular end-diastolic pressure, and the maximal rates of increase and decrease in LV pressure, respectively.