SAMHD1 Bound to Clofarabine-TP in the Catalytic Pocket and Allosteric Pocket
收藏Protein Data Bank Japan2024-03-13 更新2026-03-21 收录
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SAMHD1 Bound to Clofarabine-TP in the Catalytic Pocket and Allosteric Pocket Descriptor: 3,3',3''-phosphanetriyltripropanoic acid, 9-{2-deoxy-2-fluoro-5-O-[(R)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-arabinofuranosyl}-2-me thyl-9H-purin-6-amine, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ... Authors: Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. Deposit date: 2018-06-26 Release date: 2018-10-10 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
创建时间:
2018-06-26



