Data for: Austalides V and W, New Meroterpenoids from the Fungus Aspergillus ustus and Their Anti-Cancer Activities

This research is dedicated to the isolation and determination of the structure of two new metabolites (austalides V and W) from the austalide meroterpenoids and the study of their anticancer activity. The structures of novel metabolites were established by modern physical methods (multinuclear NMR and mass-spectrometry) and by comparison with related known compounds. The main structural feature of both compounds is a five-membered cycle (G), an unprecedented structural fragment, first found in austalides.

本研究致力于从澳斯泰德类异戊二烯类化合物中分离鉴定两种新的代谢物（澳斯泰德V和W）的结构，并研究其抗癌活性。通过现代物理方法（多核核磁共振和质谱分析）以及与已知相关化合物的比较，建立了新型代谢物的结构。这两种化合物的结构特征均为一个五元环（G），这是一个前所未有的结构片段，首次在澳斯泰德类化合物中发现。