Additional file 12: Figure S8. of Integrative genomic deconvolution of rheumatoid arthritis GWAS loci into gene and cell type associations

Network connectivity and neighborhoods of genes identified through overlap with enhancers and active genes in primary B cell, T cell, and monocyte datasets. A Network connectivity parameters compared for GWAS-associated genes identified in this study compared to those annotated by NCBI phenotype-genotype integrator. B Enrichment of interactome subnetwork genes in cell types and canonical pathways. C Subnetwork of genes that were found to be unique to T cells. D Enrichment of T cell specific interactome subnetwork genes in cell types and canonical pathways [2, 28]. (ZIP 7.33 mb)