Human released or cell surface-associated proteins identified in the medium on top of the 3D-liver model during E. histolytica invasion (specific for the 3D-liver model with amoebae).

Proteome data after BLAST search with the H. sapiens UniProt database (samples from 9 biological replicates) and two-stage filtering (i.e. elimination of bovine matches and subtraction of proteins identified in the model without amoebae) identified 139 proteins having at least one human-specific peptide (see Table S1 and S2). Further analysis was performed to identify secreted and cell membrane-associated proteins performing a literature search and information contained in the UniProtKB/Swiss-Prot database. For the 24 proteins found, their main function (given by the UniProtKB/Swiss-Prot database) is indicated in the table. Database accession numbers are provided. The proteins were ranked according to the number of samples in which they were found (decreasing from top to bottom). Bold-labelled entries correspond to those proteins for which hepatic cells are known to be the exclusive or a main site of synthesis. The numbers given are average from all samples. PSMS is peptide spectrum matches, MW molecular weight.Human released or cell surface-associated proteins identified in the medium on top of the 3D-liver model during E. histolytica invasion (specific for the 3D-liver model with amoebae).