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Highly Diastereoselective Crown Ether Catalyzed Arylogous Michael Reaction of 3‑Aryl Phthalides

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Figshare2017-08-09 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Highly_Diastereoselective_Crown_Ether_Catalyzed_Arylogous_Michael_Reaction_of_3_Aryl_Phthalides/5293318
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The first arylogous Michael reaction of 3-aryl phthalides has been developed. The reaction, promoted by catalytic amounts of KOH or K3PO4 and dibenzo-18-crown-6, affords the corresponding 3,3-disubstituted phthalides in good to high yields and as single diastereomers in nearly all studied cases.
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2017-08-09
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