Images of evolution: origin of spontaneous RNA replication waves.
收藏PubMed Central1993-05-01 更新2026-05-16 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC46472/
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资源简介：
Self-replicating molecules set up traveling concentration waves that propagate in an aqueous enzyme solution. The velocity of each wave provides an accurate (+/- 0.1%) noninvasive measure of fitness for the RNA species currently growing in its front. Evolution may be followed from changes in the front velocity, and these differ from wave to wave. Thousands of controlled evolution reactions in traveling waves have been monitored in parallel to obtain quantitative images of the stochastic process of natural selection. An RNA polymerase (RNA-dependent RNA nucleotidyltransferase, EC 2.7.7.6), extracted from bacteria infected by the Q beta RNA virus, catalyzes the replication. The traveling waves that arise spontaneously without added RNA provide a model system for major evolutionary change. IMAGES:
提供机构：
National Academy of Sciences
创建时间：
1993-05-01
