Reidl2006_CalciumOscillationInCilia

This a model from the article:
Model of calcium oscillations due to negative feedback in olfactory cilia.

Reidl J, Borowski P, Sensse A, Starke J, Zapotocky M, Eiswirth M. Biophys J.
2006;90(4):1147-55. 16326896
,
Abstract:

We present a mathematical model for calcium oscillations in the cilia of olfactory sensory neurons. The underlying mechanism is based on direct negative regulation of cyclic nucleotide-gated channels by calcium/calmodulin and does not require any autocatalysis such as calcium-induced calcium release. The model is in quantitative agreement with available experimental data, both with respect to oscillations and to fast adaptation. We give predictions for the ranges of parameters in which oscillations should be observable. Relevance of the model to calcium oscillations in other systems is discussed.
This model was taken from the CellML repository
and automatically converted to SBML.
The original model was:
reidl, borowski, sensse, starke, zapotocky, eiswirth (2006) - version03

The original CellML model was created by:
Nunns, Geoffrey, Rogan

[e-mail]
The University of Auckland
Auckland Bioengineering Institute
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