SOX2 expression in relation to clinicopathological characteristics in CRC.

Abbreviations: MSI, microsatellite instability; MSS, microsatellite stable; CIMP, CpG island methylator phenotype (according to an eight-gene CIMP panel). aχ2 test. bThe following numbers of missing cases were present: TNM stage, 12; localization, 5; grade, 7; MSI screening status, 15; CIMP status, 4; BRAF V600E, 8; KRAS, 7. cCIMP negative, no promoter hypermethylation; CIMP low, one to five genes methylated; CIMP high, six to eight genes methylated.