ABCAs mediate lipid efflux
收藏reactome.org2025-03-22 收录
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The exact roles of ABCA2 (Vulevic et al. 2001, Kaminski et al. 2001), ABCA6 (Kaminski & Wenzel et al. 2001), ABCA9 (Piehler et al. 2002) and ABCA10 (Wenzel et al. 2003), candidates for ABC lipid transporter-related activities, need to be elucidated. Even thought cholesterol-responsiveness has been noted in experimental systems, contribution of these proteins in regulation or in active transport is not yet clear.
关于ABCA2(Vulevic等,2001年,Kaminski等,2001年)、ABCA6(Kaminski & Wenzel等,2001年)、ABCA9(Piehler等,2002年)以及ABCA10(Wenzel等,2003年),这些被认定为AB脂质转运相关活动的候选蛋白,其确切作用机制尚待阐明。尽管在实验体系中胆固醇的敏感性已有所观察,但这些蛋白在调节或主动转运过程中的贡献尚不明确。
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